Cov tshuaj tiv thaiv oxidation yog cov tshuaj tiv thaiv tseem ceeb hauv cov organic chemistry. Hauv xyoo tas los no, cyclodextrins tau siv dav hauv cov tshuaj tiv thaiv oxidation. Cyclodextrins, raws li supramolecular catalysts, muaj cov nyhuv ntawm kev ceev cov tshuaj tiv thaiv kom lub sij hawm cov tshuaj tiv thaiv txo. Chen et al. kawm txog oxidation cov tshuaj tiv thaiv ntawm cinnamicaldehyde siv -CDraws li tus catalyst (Scheme 1a). Cinnamaldehyde thiab -CD tuaj yeem tsim cov kev sib koom ua ke nrog cov molar piv ntawm 1: 1 hauv dej, thiab tus nqi ntawm nucleophilic oxidation nyob rau hauv lub xub ntiag ntawm -CD tau nrawm dua li qhov tsis muaj catalyst. Tsis tas li ntawd, cov txiaj ntsig ntawm benzaldehyde tau nce mus txog 69% ntawm 333 K. Lub tswv yim mechanism ntawm oxidation ntawm cinnamicaldehyde tau qhia hauv Scheme 1b.
Scheme 1. (a) Cov tshuaj tiv thaiv oxidation ntawm cinnamaldehyde catalyzed los ntawm -CD;
(b) cov txheej txheem ntawm oxidation ntawm cinnamaldehyde catalyzed los ntawm -CD.
Muaj tseeb tiag, nws yog ib qho tseem ceeb thiab muaj txiaj ntsig uas cov tshuaj tiv thaiv tuaj yeem ua tau raws li qhov mob me me, zam qee qhov kev tawm tsam. Ji et al. kawm txog cov tshuaj tiv thaiv ntawm cov cawv oxidized rau aldehydes nyob rau hauv cov mob me, xaiv cov reactants zoo thiab pheej yig (Scheme 2a). Vim tias muaj peev xwm tsim cov kev sib xyaw ua ke ntawm cyclodextrins thiab cov reactants, cov tshuaj tiv thaiv yog homogeneous, uas yog qhov zoo rau kev nce qib ntawm cov tshuaj tiv thaiv. Lub substrate Scope ntawm cov cawv tau nthuav dav kom suav nrog cov cawv uas muaj ntxhiab tsw zoo hauv cov txiaj ntsig zoo. Qhov zoo ntawm cov tshuaj tiv thaiv no muaj nyob rau hauv pheej yig reactants thiab recycle catalysts ntawm cyclodextrins. Ntawm qhov tod tes, cov txheej txheem ntawm oxidation ntawm cawv tau npaj siab (Tebchaws 2b).
Tswv yim 2. (a) Cov tshuaj tiv thaiv oxidation ntawm cawv catalyzed los ntawm CDs; (b) lub tswv yim tshuaj tiv thaiv mechanism ntawm cawv oxidized rau aldehyde.
