Paeonol, lub ntuj polyphenolic compound, nthuav tawm ntau yam kev ua ub no, nrog rau nws cov tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob tshwj xeeb tshwj xeeb:
Anti-inflammatory teebmeem:
Paeonol tuaj yeem cuam tshuam kev ua haujlwm ntawm cov enzymes inflammatory xws li cyclooxygenase-2 (COX-2) thiab 5-lipoxygenase, yog li inhibiting zus tau tej cov pro-inflammatory mediators xws li prostaglandins thiab leukotrienes, exerting anti- inflammatory teebmeem.
Kev tshawb fawb tau pom tias paeonol tuaj yeem hloov kho qhov kev qhia ntawm cytokines inflammatory, xws li IL-6 thiab TNF- , thiab inhibit NF-κB signaling pathway, yog li txo cov inflammatory teb.
Cov kev sim tsiaj tau pom tias paeonol muaj qhov cuam tshuam loj heev rau ob qho tib si mob thiab mob ntev, ua kom pom nws qhov dav-spectrum anti-inflammatory zog.
Cov teebmeem analgesic (pain-relieving):
Paeonol tuaj yeem cuam tshuam kev tso tawm ntawm cov neurotransmitters, xws li tshuaj P thiab CGRP, yog li thaiv kev sib kis ntawm cov kab mob inflammatory thiab mob.
Tsis tas li ntawd, paeonol tuaj yeem hloov kho qhov endogenous opioid receptor system, txhim kho cov teebmeem ntawm cov tshuaj analgesic, yog li ua haujlwm ncaj qha rau qhov mob.
Cov kev tshawb fawb ua ntej tau ua pov thawj tias paeonol nthuav tawm cov kev ua haujlwm zoo heev hauv cov qauv mob, xws li mob neuropathic thiab mob caj dab.
Hauv cov ntsiab lus, cov tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob ntawm paeonol muab lub hauv paus ruaj khov rau nws cov kev siv peev xwm hauv kev tswj qhov mob thiab kho cov kab mob inflammatory. Nrog rau qhov tshwm sim ntawm dej-soluble paeonol, kev kho mob txhais lus ntawm cov khoom muaj feem xyuam yuav tsum tau ua kom nrawm dua.
