NOVEL SMART HYDROGEL muab cov kev kho mob tshwj xeeb rau PERIODONTITIS
Ib pab neeg tshawb fawb Suav tau ua tiav ib qho ntse hydrogel integrating injectability, self- kho, thiab antibacterial zog, muab ib tug tshiab kev daws teeb meem rau periodontitis. Kev tshawb fawb, ua tiav los ntawm Qiu Jingping, Lan Jue, thiab lawv pab neeg, tau luam tawm nyob rau hauv ib lub npe nrov thoob ntiaj teb kev kawm phau ntawv journal.
Periodontitis yog ib hom kab mob sib kis kab mob. Cov txheej txheem kev kho mob ib txwm ntsib cov kev txwv xws li kev siv tshuaj tsis txaus hauv zos thiab xav tau ntau yam kev kho mob. Thaum cov tshuaj txhaj tshuaj hydrogel uas twb muaj lawm tuaj yeem hloov mus rau qhov tsis xwm yeem ntawm cov hnab ris hauv lub sijhawm, lawv feem ntau raug kev txom nyem los ntawm cov neeg kho tshuab tsis zoo thiab tsis muaj tus kheej - kho muaj peev xwm, ua rau lawv tsis txaus rau qhov chaw ntawm qhov ncauj.
Pab neeg tshiab tau tsim kho dual -cov qauv sib txuas sib txuas los ntawm kev sib txuas hydroxypropyl chitosan nrog polyvinyl cawv, ua rau muaj kev ua tau zoo ntawm - cov khoom siv hydrogel. Kev sim cov ntaub ntawv qhia tau hais tias cov khoom no ua tiav lub zog txhua yam ntawm 18.2 KPa, ib qho tshuaj tua kab mob ntau tshaj 85% tawm tsam E. coli thiab S. aureus, thiab tso cai rau cov tshuaj tso tawm mus txog 168 teev. Tau txais txiaj ntsig los ntawm kev sib koom ua ke ntawm kev sib koom ua ke dynamic covalent bonds, cov hydrogel kuj pom zoo rau tus kheej - kho muaj peev xwm thiab txhaj tshuaj.
Txoj kev vam meej ntawm qhov ntse hydrogel no tsis yog tsuas yog muab lub tswv yim zoo dua hauv zos xa tshuaj rau kev kho mob periodontitis, tab sis nws cov khoom siv tshiab tsim lub tswv yim kuj tseem muaj txiaj ntsig zoo rau kev siv thev naus laus zis hauv lwm cov ntaub so ntswg engineering thiab kev xa tshuaj. Cov kws tshawb fawb tau hais tias lub tshuab thev naus laus zis no muaj peev xwm nthuav dav rau ntau thaj chaw biomedical, xws li kho qhov txhab thiab pob txha mos.
